Do you want to see if there are any clinical trials studying your condition? Your neurologist may even be leading one. The Department of Neurology has a number of studies currently recruiting, which you can browse here.
Our Actively Enrolling Clinical Trials | International Clinical Trials Day 2023
Clinical Trials by Condition
- ALS
- Alzheimer’s Disease, Early
- Apoplexy
- Asthma
- Atrial Fibrillation
- Carotid Stenosis
- Cognitive Impairment
- COVID
- Degenerative Lumbar Spinal Stenosis
- Development and Epileptic Encephalopathy
- Dravet Syndrome
- Drug-Resistant Focal Onset Seizures
- Dystonia
- Encephalitis
- Essential Tremor
- Facioscapulohumeral Muscular Dystrophy (FSHD)
- Focal Epilepsy
- GNE Myopathy
- Hyperlipoproteinemia(a)
- Internal Carotid Artery Stenosis
- Intracranial Arteriosclerosis
- Ischemic Stroke
- Lennox Gastaut Syndrome
- Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis
- Migraine
- MS
- MS, Relapsing
- Myasthenia Gravis
- Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOG-AD)
- Neuromyelitis Optica Spectrum Disorder
- Painful Diabetic Peripheral Neuropathy
- Parkinson's Disease
- Refractory Epilepsy
- Sleep Apnea
- Stereotypical Prolonged Seizures
- Stroke
- Temporal Lobe Epilepsy
- Transient Ischemic Attack (TIA)
Clinical Trials by Provider
Clinical Trials by Condition
ALS
Recruiting
- "Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS) (HIMALAYA)" | PI Mark Bromberg, MD, PhD
- "Radicava® (Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)" | PI Summer Gibson, MD
- "A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic Mutation (ALSpire)" | PI Summer Gibson, MD
- "A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS)" | PI Summer Gibson, MD
- "HEALEY ALS Platform Trial - Master Protocol" | PI Summer Gibson, MD
Alzheimer’s Disease, Early
Active, Not Recruiting
- "A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease (Clarity AD)" | PI John Rose, MD
Apoplexy
- "UR-Strokes Trial Renewal" | PI Jennifer Majersik, MD
Asthma
Recruiting
- "PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study" | PI Stephanie Lyden, MD
Atrial Fibrillation
Recruiting
- "Anticoagulation in ICH Survivors for Stroke Prevention and Recovery (ASPIRE)" | PI Nabeel Chauhan, MD
Carotid Stenosis
Recruiting
- "Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)" | PI Jennifer Majersik, MD
Cognitive Impairment
Recruiting
- "Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H) (CREST-H)" | PI Jennifer Majersik, MD
COVID
Active, Not Recruiting
- "Trial of Treatments for COVID-19 in Hospitalized Adults (DisCoVeRy)" | PI Jennifer Majersik, MD
Degenerative Lumbar Spinal Stenosis
- "DLSS Discover and Validation" | PI J. Rob Singleton, MD
Development and Epileptic Encephalopathy
Recruiting
- "Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies (PACIFIC)" | PI Amir Arain, MD
Dravet Syndrome
Recruiting
- "Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies (PACIFIC)" | PI Amir Arain, MD
Drug-Resistant Focal Onset Seizures
Recruiting
- "Realize Trial for Drug Resistant Focal Onset Seizures" | PI Amir Arain, MD
Dystonia
Recruiting
- "Abbott DBS Post-Market Study of Outcomes for Indications Over Time (ADROIT)" | PI Paolo Moretti, MD
Encephalitis
Recruiting
- "The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis (ExTINGUISH)" | PI Stacey Clardy, MD, PhD
Essential Tremor
Recruiting
- "Abbott DBS Post-Market Study of Outcomes for Indications Over Time (ADROIT)" | PI Paolo Moretti, MD
Facioscapulohumeral Muscular Dystrophy (FSHD)
Recruiting
- "Efficacy and Safety of Losmapimod in Treating Patients With Facioscapulohumeral Muscular Dystrophy (FSHD) (Reach)" | PI Summer Gibson, MD
Focal Epilepsy
Active, Not Recruiting
- "A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy (X-TOLE)" | PI Amir Arain, MD
GNE Myopathy
Recruiting
- "Multi-Center Study of ManNAc for GNE Myopathy (MAGiNE)" | PI J. Rob Singleton
Hyperlipoproteinemia(a)
Recruiting
Internal Carotid Artery Stenosis
Recruiting
- "Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H) (CREST-H)" | PI Jennifer Majersik, MD
Intracranial Arteriosclerosis
Recruiting
- "Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)" | PI Jennifer Majersik, MD
- "Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study" | PI Jennifer Majersik, MD
Ischemic Stroke
Not Yet Recruiting
- "Efficacy and Safety Evaluation of 3K3A-APC in Ischemic Stroke (RHAPSODY-2)" | PI Jennifer Majersik, MD
Recruiting
- "Sleep for Stroke Management and Recovery Trial (Sleep SMART)" | PI Jana Wold, MD
- "MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study (MASTERS-2)" | PI Dana DeWitt, MD
Lennox Gastaut Syndrome
Recruiting
- "Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies (PACIFIC)" | PI Amir Arain, MD
Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis
Recruiting
- "FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy" | PI Amir Arain, MD
Migraine
- "Sensory Amplifications as Biomarkers of Migraine Progression" | PIs Melissa Cortez, DO, and KC Brennan, MD
MS
Recruiting
- "Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial (TREAT-MS)" | PI John Rose, MD
- "Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis (NEOS)" | PI M. Mateo Paz Soldan, MD
MS, Relapsing
Recruiting
- "Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis" | PI M. Mateo Paz Soldan, MD
Myasthenia Gravis
Recruiting
- "Myasthenia Gravis Inebilizumab Trial (MINT)" | PI Kyle Mahoney, MD
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOG-AD)
Recruiting
- "A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD) (cosMOG)" | PI Stacey Clardy, MD, PhD
Neuromyelitis Optica Spectrum Disorder
Enrolling by Invitation
- "CorEvitas SPHERES (Synergy of Prospective Health & Experimental Research for Emerging Solutions) Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD)" | PI Stacey Clardy, MD, PhD
Painful Diabetic Peripheral Neuropathy
Recruiting
- "EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA (EN21-01)" | PI J. Rob Singleton, MD
Parkinson's Disease
Recruiting
- "Abbott DBS Post-Market Study of Outcomes for Indications Over Time (ADROIT)" | PI Paolo Moretti, MD
Enrolling by Invitation
- "Study To Assess Adverse Events and Change in Disease Activity Of 24-hour Continuous Subcutaneous Infusion Of ABBV-951 In Adult Participants With Advanced Parkinson's Disease" | PI Paolo Moretti, MD
Refractory Epilepsy
Recruiting
- "Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy" | PI Amir Arain, MD
Sleep Apnea
Recruiting
- "Sleep for Stroke Management and Recovery Trial (Sleep SMART)" | PI Jana Wold, MD
Stereotypical Prolonged Seizures
Enrolling by Invitation
- "A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures" | PI Angela Peters, MD
Stroke
Recruiting
- "Sleep for Stroke Management and Recovery Trial (Sleep SMART)" | PI Jana Wold, MD
Temporal Lobe Epilepsy
- "Stereotactic Laser Ablation for Temporal Lobe Epilepsy (SLATE)" | PI Amir Arain, MD
Transient Ischemic Attack (TIA)
Recruiting
- "Sleep for Stroke Management and Recovery Trial (Sleep SMART)" | PI Jana Wold, MD
Clinical Trials by Provider
Arain, Amir
- "Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies (PACIFIC)" | PI Amir Arain, MD
- "Realize Trial for Drug Resistant Focal Onset Seizures" | PI Amir Arain, MD
- "A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy (X-TOLE)" | PI Amir Arain, MD
- "FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy" | PI Amir Arain, MD
- "Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy" | PI Amir Arain, MD
- "Stereotactic Laser Ablation for Temporal Lobe Epilepsy (SLATE)" | PI Amir Arain, MD
Brennan, KC
- "Sensory Amplifications as Biomarkers of Migraine Progression" | PIs Melissa Cortez, DO; KC Brennan, MD
Bromberg, Mark
- "Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS) (HIMALAYA)" | PI Mark Bromberg, MD, PhD
Chauhan, Nabeel
- "Anticoagulation in ICH Survivors for Stroke Prevention and Recovery (ASPIRE)" | PI Nabeel Chauhan, MD
Clardy, Stacey
- "The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis (ExTINGUISH)" | PI Stacey Clardy, MD, PhD
- "A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD) (cosMOG)" | PI Stacey Clardy, MD, PhD
- "CorEvitas SPHERES (Synergy of Prospective Health & Experimental Research for Emerging Solutions) Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD)" | PI Stacey Clardy, MD, PhD
Cortez, Melissa
- "Sensory Amplifications as Biomarkers of Migraine Progression" | PIs Melissa Cortez, DO; KC Brennan, MD
DeWitt, Dana
- "MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study (MASTERS-2)" | PI Dana DeWitt, MD
Gibson, Summer
- "Radicava® (Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)" | PI Summer Gibson, MD
- "A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic Mutation (ALSpire)" | PI Summer Gibson, MD
- "A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS)" | PI Summer Gibson, MD
- "HEALEY ALS Platform Trial - Master Protocol" | PI Summer Gibson, MD
- "Efficacy and Safety of Losmapimod in Treating Patients With Facioscapulohumeral Muscular Dystrophy (FSHD) (Reach)" | PI Summer Gibson, MD
Lyden, Stephanie
- "PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study" | PI Stephanie Lyden, MD
Mahoney, Kyle
- "Myasthenia Gravis Inebilizumab Trial (MINT)" | PI Kyle Mahoney, MD
Majersik, Jennifer
- "UR-Strokes Trial Renewal" | PI Jennifer Majersik, MD
- "Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)" | PI Jennifer Majersik, MD
- "Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H) (CREST-H)" | PI Jennifer Majersik, MD
- "Trial of Treatments for COVID-19 in Hospitalized Adults (DisCoVeRy)" | PI Jennifer Majersik, MD
- "Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)" | PI Jennifer Majersik, MD
- "Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study" | PI Jennifer Majersik, MD
- "Efficacy and Safety Evaluation of 3K3A-APC in Ischemic Stroke (RHAPSODY-2)" | PI Jennifer Majersik, MD
Moretti, Paolo
- "Abbott DBS Post-Market Study of Outcomes for Indications Over Time (ADROIT)" | PI Paolo Moretti, MD
- "Study To Assess Adverse Events and Change in Disease Activity Of 24-hour Continuous Subcutaneous Infusion Of ABBV-951 In Adult Participants With Advanced Parkinson's Disease" | PI Paolo Moretti, MD
Paz Soldan, M. Mateo
- "Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis (NEOS)" | PI M. Mateo Paz Soldan, MD
Peters, Angela
- "A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures" | PI Angela Peters, MD
Rose, John
- "A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease (Clarity AD)" | PI John Rose, MD
- "Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial (TREAT-MS)" | PI John Rose, MD
Singleton, J. Robinson
- "DLSS Discovery and Validation" | PI J. Rob Singleton, MD
- "Multi-Center Study of ManNAc for GNE Myopathy (MAGiNE)" | PI J. Rob Singleton
- "EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA (EN21-01)" | PI J. Rob Singleton, MD
Tekiela, Piotr
Wold, Jana
- "Sleep for Stroke Management and Recovery Trial (Sleep SMART)" | PI Jana Wold, MD